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Cancer Topics Index 05/02/2016(Daily Test version/ 日刊テスト版)No.21

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Cancer Topics Index 05/02/2016(Daily Test version/ 日刊テスト版) No.21

Flags 【海外:overseas】
◇NCI (National Cancer Institute)◇
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【ブルーリボンパネルは、作業を開始】
The Cancer Community's Next Steps for the Moonshot Initiative (April 29, 2016 by Dinah Singer, Ph.D.)
At last week's annual meeting of the American Association for Cancer Research, Vice President Biden's historic address to more than 4,000 researchers in attendance made clear that he and President Obama agree with many of us in the research community: We are at a critical juncture where the convergence of expanded knowledge and a more detailed understanding of cancer, the availability of advanced technologies, and a national commitment to collaborating in new ways has produced an unprecedented opportunity for rapidly accelerating progress against cancer.

logo-clinicaltrials-gov.png
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※2週間前の情報を基準として掲載。一部の記事(がんと直接関連しないもの)は割愛しています。
17 studies found for: cancer | received from 04/16/2016 to 04/18/2016

【乳がん】
1 Recruiting
Pink Warrior—Support Group Toolkit for Breast Cancer Survivors
Conditions: Breast Cancer; Physical Activity
Interventions: Behavioral: Active video game-based intervention; Behavioral: Pedometer
Sponsor:The University of Texas Medical Branch, Galveston
ClinicalTrials.gov Identifier:NCT02750241

【食道がん】
2 Recruiting
Endostatin in Combination With Oxaliplatin and Radiotherapy in Esophageal Cancer Patients.
Conditions: Esophageal Cancer; Endostatin
Interventions: Drug: Endostatins; Drug: Oxaliplatin; Radiation: Radiotherapy
Sponsor:Hangzhou Cancer Hospital
ClinicalTrials.gov Identifier:NCT02745561

【神経芽腫】
3 Recruiting
A Combined Cell Therapy Approach to the Treatment of Neuroblastoma
Conditions: Neuroblastoma; Neoplasms, Nerve Tissue
Interventions: Procedure: Autologous Hematopoietic Progenitor Cell Transplant; Biological: KLH and Tumor Lysate Pulsed DC Vaccine
Sponsor:H. Lee Moffitt Cancer Center and Research Institute
ClinicalTrials.gov Identifier:NCT02745756

【乳がん/リンパ浮腫】
4 Not yet recruiting
Reliability and Validity of Self-measured Arm Circumference in Women With Breast Cancer
Conditions: Lymphedema; Breast Cancer
Intervention: Procedure: Self-measured arm circumference, therapist-measured arm-circumference, perometer-measured arm circumference
Sponsor:University of British Columbia
ClinicalTrials.gov Identifier:NCT02752659

【がん/意思決定援助(PDA)】
5 Not yet recruiting
Development and Evaluation of a Fertility Preservation Patient Decision Aid for Women With Cancer.
Condition: Cancer
Intervention:
Sponsor:University of Sheffield
ClinicalTrials.gov Identifier:NCT02753296

【直腸がん】
6 Completed
Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer
Condition: Rectal Neoplasms
Interventions: Radiation: VMAT-SIB; Drug: XELOX
Sponsor:Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
ClinicalTrials.gov Identifier:NCT02745639

【血液がん】
7 Not yet recruiting
Phase I Trial of BAY1251152 for Advanced Blood Cancers
Condition: Hematologic Neoplasms
Intervention: Drug: BAY1251152
Sponsor:Bayer
ClinicalTrials.gov Identifier:NCT02745743

【大腸がん/マントル細胞リンパ腫】
8 Not yet recruiting
A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents
Conditions: Advanced Cancer; Colorectal Cancer; Mantle Cell Lymphoma
Interventions: Drug: Ramucirumab; Drug: Merestinib; Drug: Abemaciclib
Sponsor:Eli Lilly and Company
ClinicalTrials.gov Identifier:NCT02745769

【膀胱がん】
9 Not yet recruiting
A Study of Rapamycin Combined With Intravesical BCG in Patients With Non-muscle Invasive Bladder Cancer
Condition: Bladder Cancer
Intervention: Drug: Sirolimus
Sponsor:The University of Texas Health Science Center at San Antonio
ClinicalTrials.gov Identifier:NCT02753309

【肝細胞がん】
10 Enrolling by invitation
DEB-TACE for Hepatocellular Carcinoma
Condition: Hepatocellular Carcinoma
Intervention: Procedure: DEB-TACE
Sponsor:Surefire Medical, Inc.
ClinicalTrials.gov Identifier:NCT02748161

【骨髄異形成症候群/急性骨髄性白血病】
11 Enrolling by invitation
Peptide Vaccination in Combination With Azacitidine for Patients With MDS and AML
Conditions: Myelodysplastic Syndrome; Acute Myeloid Leukemia
Interventions: Biological: NPMW-peptide vaccine; Drug: Azacitidine
Sponsor:Inge Høgh Dufva
ClinicalTrials.gov Identifier:NCT02750995

【乳がん/ER+ and AR+】
12 Not yet recruiting
Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass
Condition: ER+ and AR+ Breast Cancer
Intervention: Drug: GTx-024 9 or 18 mg
Sponsor:GTx
ClinicalTrials.gov Identifier:NCT02746328

【乳房切除術】
13 Completed
Paravertebral Block (PVB) Combined Pectoral Musculature Blocks for Modified Radical Mastectomy (MRM)
Condition: Mastectomy, Modified Radical
Intervention:
Sponsor:Sun Yat-sen University
ClinicalTrials.gov Identifier:NCT02747992

【造血幹細胞移植】
14 Not yet recruiting
Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation
Conditions: Acute Myeloid Leukemia; Myelodysplastic Syndrome; Acute Lymphocytic Leukemia
Interventions: Drug: Fludarabine; Radiation: Fractionated total body irradiation; Drug: Busulfan; Drug: Cyclophosphamide; Radiation: Single dose total body irradiation; Drug: Melphalan; Drug: Granulocyte-colony stimulating factor; Procedure: Stem cell transplant; Drug: Azacitidine
Sponsor:Washington University School of Medicine
ClinicalTrials.gov Identifier:NCT02750254

【びまん性大細胞型B細胞リンパ腫】
15 Recruiting
An Evaluation AZD2014 Alone and in Combination With Rituximab in Relapsed/Refractory Diffuse Large B Cell Lymphoma
Condition: Diffuse Large B-Cell Lymphoma
Interventions: Drug: AZD 2014; Drug: Rituximab
Sponsor:University of Birmingham
ClinicalTrials.gov Identifier:NCT02752204

【頭頸部扁平上皮がん】
16 Not yet recruiting
Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy
Condition: Carcinoma, Squamous Cell of Head and Neck
Interventions: Drug: Cetuximab; Radiation: radiation; Drug: Docetaxel; Drug: Cisplatin
Sponsor:Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
ClinicalTrials.gov Identifier:NCT02753140

【造血幹細胞移植】
17 Active, not recruiting
Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
Conditions: Myelodysplastic Syndrome; Allogeneic Hematopoietic Stem Cell Transplantation; Conditioning
Interventions: Drug: Decitabine; Drug: Busulfan (BU); Drug: Cyclophosphamide (CY)
Sponsor:Nanfang Hospital of Southern Medical University
ClinicalTrials.gov Identifier:NCT02744742

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◇EU, EMA, CHMP, Cancer Research UK, NICE◇
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【News digest】
News digest – e-cigarettes, Chernobyl, ‘moonshots’ and… canned food? (April 30, 2016 Nick Peel Science blog)

<Medical Journal & Other News>
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【Hsp90阻害剤による薬剤耐性前立腺がんの治療】JOURNAL:Cancer Research
New cancer drugs could treat lethal resistant prostate cancers (05/01/2016 EurekAlert!/INSTITUTE OF CANCER RESEARCH)
Men with aggressive prostate cancer that has stopped responding to conventional treatment could potentially benefit from a new class of cancer drug designed to overcome drug resistance, a new study suggests.Researchers found that the drugs, called Hsp90 inhibitors, specifically target and inactivate a mechanism commonly used by prostate cancer cells to evade the effects of standard treatment.The findings provide vital information about the role of Hsp90 in drug-resistant prostate cancers, and open up potential new routes to cancer treatment based on blocking this or related proteins.

【ステージ第IIa精巣がん患者には、化学療法より放射線療法が効果的】JOURNAL:Clinical Oncology
Radiotherapy more effective than chemotherapy for early stage II testicular cancer (05/01/2016 EurekAlert!/EUROPEAN SOCIETY FOR RADIOTHERAPY AND ONCOLOGY; ESTRO)
Turin, Italy: A large study of testicular cancer patients has shown that radiation therapy is a better treatment than chemotherapy for patients with stage IIa disease (where one or more regional lymph nodes contain cancer cells but they are less than 2cms in diameter).These findings, presented at the ESTRO 35 conference today (Monday) and published simultaneously in Clinical Oncology [1], are important because, until now, there has been little evidence about which treatment for testicular seminoma is more effective, and there has been a tendency to move away from radiation therapy towards chemotherapy for treating stage IIa-b patients. Guidelines from the US National Cancer Comprehensive Network recommend radiotherapy for stage IIa, while those from the European Association of Urology allow for either radiation therapy or chemotherapy; both sets of guidelines are equivocal for stage IIb.

【多発性骨髄腫】
Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma (April 28, 2016 The New England Journal of Medicine)
多発性骨髄腫に対する経口イキサゾミブ,レナリドミド,デキサメタゾン (April 28, 2016 Vol. 374 No. 17 南江堂洋書部:日本語)
A Phase 3 Study Comparing Oral Ixazomib Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Relapsed and/or Refractory Multiple Myeloma (First received: March 22, 2012 ClinicalTrials.gov Identifier:NCT01564537)

【Smart therapy】
がん細胞への攻撃を支援するソフトウェアを提供する新企業「ヴィトルヴィアン・ネットワークス」とは? (Apr 26, 2016 GE REPORTS JAPAN)
Vitruvian Networks (website)

【ロックと抗がん剤】
Thunderous rock music improves cancer drug delivery (1 April 2016 MNT)
ロックが抗がん剤の副作用を無くす? 音楽の新しすぎる可能性 (04/30/2016 CIRCL)

【睡眠時無呼吸症候群】
Sleep apnea may drive tumor growth by promoting blood vessel formation (12 March 2016 MNT)
新発見。睡眠時無呼吸症候群ががん細胞の増殖を許していた (05/01/2016 CIRCL)

Graphics 【日本国内:Japan】
<Press Release:日本国内>
【がん検診アンケート調査】
癌の検診に対しての意識を調査、どのようながん検診・検査を受けている人が多いのか? (04/30/2016 iMedi)

<News>
【心臓腫瘍】
ひたむきに生きて サッちゃんに教わった=天野篤・順天堂医院院長 (05/01/2016 毎日新聞)

【腫瘍溶解ウイルス】
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オンコリスが苦難を越えて実現目指す、がん細胞を溶かす治療薬(上)(04/30/2016 会社四季報Online)

【患者格差】
日本人の9割は2流? “患者格差”はどこで生まれるのか テキサス大学MDアンダーソンがんセンター上野直人医師 (04/29/2016 dot.)

【在宅医療】
「"死ぬまで、どう生きるか"を選択しよう」佐々木淳さんに聞く、これからの在宅医療 (04/29/2016 ハフィントン・ポスト)

<新刊メタデータ:New Books>
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【タイトル】がん放置実践実録 Vol.2 (乳がん)
著者:久保園 和巳/単行本(ソフトカバー): 112ページ/出版社: ブイツーソリューション (2016/4/30)/ISBN-10: 4864764026/ISBN-13: 978-4864764025/¥432

【タイトル】白い洋梨 Kindle版 (小説)
著者:時枝 文彦/フォーマット: Kindle版/ファイルサイズ: 65536 KB/同時に利用できる端末数: 無制限/販売: Amazon Services International, Inc./ASIN: B01F1NH7A6/¥510

<雑誌記事:Magazine/Medical journal>
Stockholm Public Library
◆月刊薬事 (Vol.58 No.7)/じほう/発売日:2016年4月30日/価格(税込):2,160円
【タイトル】特集 薬剤師目線で実践する経口抗がん薬マネジメント
 気になる新薬マネジメント、がん患者指導管理や薬薬連携のコツを紹介!
・特集にあたって  遠藤 一司
・経口抗がん薬――分類とその特徴について  石川 和宏
・アファチニブの特徴と薬学的管理のポイントは?  浅野 裕紀
・レンバチニブの特徴と薬学的管理のポイントは?  鈴木 真也
・トリフルリジン・チピラシルの特徴と薬学的管理のポイントは?  秋山 加菜
・ニボルマブの特徴と薬学的管理のポイントは?  池見 泰明、山本 将太、松原 和夫
・がん患者指導管理はどうやって始めればよい?
 薬剤師外来でのがん患者指導管理料3算定への取り組み  川澄 賢司
 薬剤師外来の運用と有用性の評価  小川 千晶
 診察前面談における副作用のモニタリングとアセスメント  組橋 由記
・上手くいく薬薬連携のコツは?
 FAXを活用した双方向性の情報共有  黒岩 勇人、眞継 賢一、上田 綾佳、倉橋 基尚、濱口 良彦
 がん化学療法支援ツールの共有による地域の薬薬連携  谷沢 克弥
 情報共有ツールの活用と学習課題を明確化した勉強会  竹内 雅代
 薬局から始める取り組みで外来化学療法のサポートを  笹本千香子

◆臨床栄養 (Vol.128 No.5)/医歯薬出版/発売日:2016年4月30日/価格(税込):1,620円
【タイトル】スポット
・緩和ケア病棟における進行がん患者と家族の栄養サポートに対するニーズ,食に関する苦悩と体験 天野晃滋

◆日経ヘルス (2016年6月号)/日経BP社/発売日:2016年4月30日/価格(税込):600円
【タイトル】がん予防の基礎講座
・がんと遺伝 遺伝性が多い乳がん、卵巣がん リスクを理解し、検診を受けよう
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